醇與烯醇醚的交換反應(yīng)
實(shí)例一
To a 0.1 M solution of 1-phenylbut-2-yn-1-ol (1 mmol) in ethylvinyl ether was added to
0.6 mmol of mercuric acetate. The reaction mixture was refluxed at 45 °C for 12 hours before quenching with a saturated aqueous sodium carbonate solution. The organic phase was extracted using diethyl ether and dried over anhydrous potassium carbonate. The solvent was removed under vacuum and the crude vinyl ether was purified on alumina gel column using hexane as aneluent. Vinyl ether was obtained in 60% yield (0.1g).
醇與烯醇醚的交換反應(yīng)
實(shí)例一
To a 0.1 M solution of 1-phenylbut-2-yn-1-ol (1 mmol) in ethylvinyl ether was added to
0.6 mmol of mercuric acetate. The reaction mixture was refluxed at 45 °C for 12 hours before quenching with a saturated aqueous sodium carbonate solution. The organic phase was extracted using diethyl ether and dried over anhydrous potassium carbonate. The solvent was removed under vacuum and the crude vinyl ether was purified on alumina gel column using hexane as aneluent. Vinyl ether was obtained in 60% yield (0.1g).
Reference: Org.Lett. 2013, 15, 4662-4665.
百度翻譯：向1-苯基-2-乙烯基-1-醇（1 mmol）的0.1 M溶液中添加
0.6 mmol醋酸汞。反應(yīng)混合物在45℃回流12小時，然后用飽和碳酸鈉水溶液淬火。有機(jī)相用乙醚萃取并在無水碳酸鉀上干燥。溶劑在真空下除去，粗乙烯基醚在氧化鋁凝膠柱上以正己烷為溶劑進(jìn)行純化。乙烯基醚的收率為60%（0.1g）。
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