酞菁（PHTHALOCYANINE）
金屬酞菁絡(luò)合物M-Pc (M=V, Mn, Fe, Co 和 Pd)是一種非常穩(wěn)定的選擇性氫化催化劑。通過控制反應(yīng)體系的化學(xué)性質(zhì)（如pH），金屬的種類等條件可以調(diào)節(jié)還原催化劑的活性。
反應(yīng)實(shí)例
p-Choroaniline (5).1 To well stirred NaBH4 (2.7 g, 70 mmol) and Co-phthalocyanine (Co-Pc) catalyst (0.5 g, 0.9 mmol) in EtOH (50 ml), 4 (1.58 g, 10 mmol) was added and the mixture was stirred for 2 h at r.t. Under ice cooling, 5 N HCl was added until pH 6-7. The catalyst was removed by filtration over a
layer of Na2SO4, the solvent was evaporated and the residue partitioned with 1N NaOH and ether. Drying and concentration of the organic layer afforded 1.22 g of 5 (96%). For reuse, the catalyst was washed with water and dried.
【Eckert H, Angew Chem Int, 1981, 20, 473】
【Eckert H, Angew Chem Int, 1986, 25, 159】
相關(guān)文獻(xiàn)
1 Eckert H Angew Chem Int 1981 20 473
2 Eckert H Angew Chem Int 1983 22 881
3 Eckert H Angew Chem Suppl 1983 1291
4 Eckert H Angew Chem Int 1986 25 159
5 Eckert H Z Natutforsch 1991 46b 339
6 Ohta S Chem Comm 2005 2134
編譯自：Organic Syntheses Based On Name Reactions, 3RdEd, A. Hassner, Page 135-136.
